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Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels

Lin, JH; Gettings, SM; Talbi, K; Schreiber, R; Taggart, MJ; Preller, M; Kunzelmann, K; Althaus, M; Gray, MA

Gray, MA (通讯作者),Newcastle Univ, Biosci Inst, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2023; 475 (2): 167

Abstract

The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel and the epithelial Na+ channel (ENaC) play essential roles in transepithe......

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