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Synthesis via the Mannich Reaction and Biological Activity of Novel Fluorinated Camptothecin Derivatives

Wang, CAH; Wang, Y; Ma, HJ; Zhu, YZ; Zhang, YM; Miao, ZY; Wu, YL

Wu, YL (corresponding author), Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China.; Miao, ZY (corresponding author), Second Mil Med Univ, Sch Pharm, 325 Guohe Rd, Shanghai 200433, Peoples R China.

CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2021; 57 (6): 704

Abstract

Two series of fluorinated camptothecin derivatives had been designed and synthesized via the Mannich reaction. The hexacyclic fluorinated camptothecin......

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