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Molecular modelling studies of quinazolinone derivatives as MMP-13 inhibitors by QSAR, molecular docking and molecular dynamics simulations techniques

Huang, SS; Feng, KR; Ren, YJ

Ren, YJ (reprint author), Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai, Peoples R China.

MEDCHEMCOMM, 2019; 10 (1): 101

Abstract

Matrix metalloproteinase-13 (MMP-13) is an attractive drug target for the treatment of osteoarthritis (OA). In this study, a series of quinazolinone d......

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