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The Polyamine Regulator AMD1 Upregulates Spermine Levels to Drive Epidermal Differentiation

Rahim, AB; Lim, HK; Tan, CYR; Jia, L; Leo, VI; Uemura, T; Hardman-Smart, J; Common, JEA; Lim, TC; Bellanger, S; Paus, R; Igarashi, K; Yang, H; Vardy, LA

Vardy, LA (corresponding author), ASTAR, Skin Res Inst Singapore, 8A Biomed Grove, Singapore 138648, Singapore.

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021; 141 (9): 2178

Abstract

Maintaining tissue homeostasis depends on a balance between cell proliferation, differentiation, and apoptosis. Within the epidermis, the levels of th......

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