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An update on CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects

Chang, WC; Hung, SI; Carleton, BC; Chung, WH

Chung, WH (corresponding author), Chang Gung Mem Hosp, Linkou & Taipei Branch, Dept Dermatol, Taipei, Taiwan.; Chung, WH (corresponding author), Chang Gung Mem Hosp, Drug Hypersensit Clin & Res, Taipei, Taiwan.; Chung, WH (corresponding author), Chang Gung Mem Hosp, Whole Genome Res Core Lab Human Dis, Taoyuan 333, Taiwan.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2020; 16 (8): 723

Abstract

Introduction Phenytoin is a frequently used drug treatment for epilepsy. Genetic polymorphisms in the metabolism of phenytoin, particularlyCYP2C9, are......

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