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New CRISPR-Cas systems from uncultivated microbes

Burstein, D; Harrington, LB; Strutt, SC; Probst, AJ; Anantharaman, K; Thomas, BC; Doudna, JA; Banfield, JF

Banfield, JF (reprint author), Univ Calif Berkeley, Dept Earth & Planetary Sci, Berkeley, CA 94720 USA.; Doudna, JA (reprint author), Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA.; Doudna, JA (reprint author), Univ Calif Berkeley, Dep

NATURE, 2017; 542 (7640): 237

Abstract

CRISPR-Cas systems provide microbes with adaptive immunity by employing short DNA sequences, termed spacers, that guide Cas proteins to cleave foreign......

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