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Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells

Onohara, T; Hisatome, I; Kurata, Y; Li, P; Notsu, T; Morikawa, K; Otani, N; Yoshida, A; Iitsuka, K; Kato, M; Miake, J; Ninomiya, H; Higaki, K; Shirayoshi, Y; Nishihara, T; Itoh, T; Nakamura, Y; Nishimura, M

Kurata, Y (reprint author), Kanazawa Med Univ, Dept Physiol 2, 1-1 Daigaku, Uchinada, Ishikawa, Japan.

JOURNAL OF ARRHYTHMIA, 2017; 33 (3): 226

Abstract

Background: Pilsicainide, classified as a relatively selective Na-(+) channel blocker, also has an inhibitory action on the rapidly-activating delayed......

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