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A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum

Yamakage, Y; Kato, M; Hongo, A; Ogino, H; Ishii, K; Ishizuka, T; Kamei, T; Tsuiji, H; Miyamoto, T; Oishi, H; Kohno, T; Hattori, M

Hattori, M (reprint author), Nagoya City Univ, Grad Sch Pharmaceut Sci, Dept Biomed Sci, Mizuho Ku, 3-1 Tanabe Dori, Nagoya, Aichi 4678603, Japan.

MOLECULAR AND CELLULAR NEUROSCIENCE, 2019; 100 ():

Abstract

Reelin plays important roles in regulating neuronal development, modulating synaptic function, and counter-acting amyloid beta toxicity. A specific pr......

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