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Dipeptide Prodrugs of the Glutamate Modulator Riluzole

Pelletier, JC; Chen, SZ; Bian, HY; Shah, R; Smith, GR; Wrobel, JE; Reitz, AB

Pelletier, JC; Reitz, AB (reprint author), Fox Chase Chem Divers Ctr Inc, 3805 Old Easton Rd, Doylestown, PA 18902 USA.; Reitz, AB (reprint author), ALS Biopharma LLC, 3805 Old Easton Rd, Doylestown, PA 18902 USA.

ACS MEDICINAL CHEMISTRY LETTERS, 2018; 9 (7): 752

Abstract

We have previously reported a prodrug strategy based on the marketed drug riluzole (2-amino-6- trifluoromethoxybenzothiazole), associated with the ben......

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