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Epac1 Signaling Pathway Mediates the Damage and Apoptosis of Inner Ear Hair Cells after Noise Exposure in a Rat Model

Sun, FF; Zhang, JG; Chen, L; Yuan, YH; Guo, XT; Dong, LY; Sun, JQ

Sun, JQ (corresponding author), First Affiliated Hosp USTC, Dept Otolaryngol Head & Neck Surg, Hefei 230001, Peoples R China.; Dong, LY (corresponding author), Anhui Med Univ, Dept Pharmacol, Key Lab Chinese Med Res & Dev State Adm Tradit Ch, Key Lab Antiinflammatory & Immunopharmacol,Minist, Hefei 230032, Peoples R China.

NEUROSCIENCE, 2021; 465 (): 116

Abstract

To investigate the role of the exchange protein directly activated by cAMP (Epac) signaling pathway in inner ear hair cell damage and apoptosis after ......

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