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Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes

Zhang, MY; Dong, Y; Hu, FX; Yang, D; Zhao, QH; Lv, C; Wang, Y; Xia, CX; Weng, QT; Liu, XF; Li, C; Zhou, PQ; Wang, TJ; Guan, YX; Guo, RQ; Liu, LJ; Geng, Y; Wu, HL; Du, J; Hu, Z; Xu, S; Chen, JK; He, AB; Liu, B; Wang, DM; Yang, YG; Wang, JY

Wang, JY (reprint author), Chinese Acad Sci, CAS Key Lab Regenerat Biol, Guangzhou, Guangdong, Peoples R China.; Wang, JY (reprint author), Chinese Acad Sci, Guangdong Prov Key Lab Stem Cell & Regenerat Med, Guangzhou Inst Biomed & Hlth, Guangzhou, Guangd

NATURE IMMUNOLOGY, 2018; 19 (3): 279

Abstract

Deletion of master regulators of the B cell lineage reprograms B cells into T cells. Here we found that the transcription factor Hoxb5, which is expre......

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