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Normalization methods for reducing interbatch effect without quality control samples in liquid chromatography-mass spectrometry-based studies

Tokareva, AO; Chagovets, VV; Kononikhin, AS; Starodubtseva, NL; Nikolaev, EN; Frankevich, VE

Starodubtseva, NL; Frankevich, VE (corresponding author), Minist Healthcare Russian Federat, Natl Med Res Ctr Obstet Gynecol & Perinatol, Moscow 117997, Russia.; Starodubtseva, NL (corresponding author), Moscow Inst Phys & Technol, Moscow 141701, Russia.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, ; ():

Abstract

Data normalization is an essential part of a large-scale untargeted mass spectrometry metabolomics analysis. Autoscaling, Pareto scaling, range scalin......

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