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Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn's Disease

Mortha, A; Remark, R; Del Valle, DM; Chuang, LS; Chai, Z; Alves, I; Azevedo, C; Gaifem, J; Martin, J; Petralia, F; Tuballes, K; Barcessat, V; Tai, SL; Huang, HH; Laface, I; Jerez, YA; Boschetti, G; Villaverde, N; Wang, MD; Korie, UM; Murray, J; Choung, RS; Sato, T; Laird, RM; Plevy, S; Rahman, A; Torres, J; Porter, C; Riddle, MS; Kenigsberg, E; Pinho, SS; Cho, JH; Merad, M; Colombel, JF; Gnjatic, S

Mortha, A (通讯作者),Univ Toronto, Dept Immunol, Med Sci Bldg,1 Kings Coll Circle,Room 7326, Toronto, ON M5S 1A8, Canada.

GASTROENTEROLOGY, 2022; 163 (3): 659

Abstract

BACKGROUND & AIMS: Anti-granulocyte macrophage-colony stimulating factor autoantibodies (aGMAbs) are detected in patients with ileal Crohn's disea......

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