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Structures and mechanisms of tRNA methylation by METTL1-WDR4

Ruiz-Arroyo, VM; Raj, R; Babu, K; Onolbaatar, O; Roberts, PH; Nam, Y

Nam, Y (通讯作者),Univ Texas Southwestern Med Ctr, Dept Biochem, Dallas, TX 75390 USA.;Nam, Y (通讯作者),Univ Texas Southwestern Med Ctr, Dept Biophys, Dallas, TX 75390 USA.;Nam, Y (通讯作者),Univ Texas Southwestern Med Ctr, Simmons Comprehens Canc Ctr, Dallas, TX 75390 USA.

NATURE, 2023; 613 (7943): 383

Abstract

Specific, regulated modification of RNAs is important for proper gene expression(1,2). tRNAs are rich with various chemical modifications that affect ......

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