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A randomized, double-blind, parallel-group phase I study comparing the pharmacokinetics, safety, and immunogenicity of LY01008, a candidate bevacizumab biosimilar, with its reference product Avastin (R) in healthy Chinese male subjects

Zhou, RP; Yang, JJ; Liu, YY; Zhang, Q; Lu, C; Tang, K; Li, X; Tang, W; Gao, EM; Wu, C; Dou, CL; Hu, W

Hu, W (通讯作者),Anhui Med Univ, Dept Clin Pharmacol, Hosp 2, Hefei, Peoples R China.

EXPERT OPINION ON BIOLOGICAL THERAPY, 2022; 22 (2): 263

Abstract

Background Bevacizumab, an inhibitor of angiogenesis, has been approved in several anti-cancer therapies. This study compared the pharmacokinetic (PK)......

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