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Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead

Grabrijan, K; Hrast, M; Proj, M; Dolsak, A; Zdovc, I; Imre, T; Petri, L; Abranyi-Balogh, P; Keseru, GM; Gobec, S

Gobec, S (通讯作者),Univ Ljubljana, Fac Pharm, Askerceva 7, Ljubljana 1000, Slovenia.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022; 243 ():

Abstract

MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) catalyzes the first committed step in the cytoplasmic part of peptidoglycan biosynthesis and is......

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