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Granulocyte colony-stimulating factor (GCSF) fused with Fc Domain produced from E. coli is less effective than Polyethylene Glycol-conjugated GCSF

Do, BH; Kang, HJ; Song, JA; Nguyen, MT; Park, S; Yoo, J; Nguyen, AN; Kwon, GG; Jang, J; Jang, M; Lee, S; So, S; Sim, S; Lee, KJ; Osborn, MJ; Choe, H

Choe, H (reprint author), Univ Ulsan, Coll Med, Asan Minnesota Inst Innovating Transplantat, Dept Physiol,Biomed Inst Technol,Asan Med Ctr, Seoul 05505, South Korea.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

Human granulocyte colony-stimulating factor (GCSF) is a well-known cytokine for neutropenia treatment. However, daily injections are required due to t......

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