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Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy

Tang, XJ; Peng, H; Xu, PF; Zhang, L; Fu, R; Tu, HJ; Guo, XR; Huang, KM; Lu, JT; Chen, H; Dong, ZQ; Dai, LJ; Luo, J; Chen, QX

Chen, QX (通讯作者),Wuhan Univ, Dept Neurosurg, Renmin Hosp, 9 Zhangzhidong Rd & 238 Jiefang Rd, Wuhan 430060, Hubei, Peoples R China.;Dai, LJ; Luo, J (通讯作者),Hubei Univ Med, Taihe Hosp, Dept Neurosurg, Shiyan 442000, Hubei, Peoples R China.

MOLECULAR THERAPY-ONCOLYTICS, 2022; 24 (): 707

Abstract

Glioblastoma (GBM) is characterized as having high molecular heterogeneity and complexity, which can be well revealed by genomic study. A truly effect......

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