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Pro-515 of the dynamin-like GTPase MxB contributes to HIV-1 inhibition by regulating MxB oligomerization and binding to HIV-1 capsid

Xu, FW; Zhao, F; Zhao, XX; Zhang, D; Liu, XM; Hu, SQ; Mei, S; Fan, ZL; Huang, Y; Sun, H; Wei, L; Wu, C; Li, QJ; Wang, JW; Cen, S; Liang, C; Guo, F

Guo, F (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Ctr AIDS Res, Beijing 100730, Peoples R China.; Guo, F (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Inst Pathogen Biol, MOH Key Lab Syst Biol Pathogens, Beijing 100730, Peoples R China.; Guo, F (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Inst Pathogen Biol, Ctr AIDS Res, Beijing 100730, Peoples R China.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2020; 295 (19): 6447

Abstract

Interferon-regulated myxovirus resistance protein B (MxB) is an interferon-induced GTPase belonging to the dynamin superfamily. It inhibits infection ......

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