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A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis

Park, SK; Zhou, XR; Pendleton, KE; Hunter, OV; Kohler, JJ; O'Donnell, KA; Conrad, NK

Conrad, NK (reprint author), Univ Texas Southwestern Med Ctr Dallas, Dept Microbiol, Dallas, TX 75390 USA.; Conrad, NK (reprint author), Univ Texas Southwestern Med Ctr Dallas, Harold C Simmons Comprehens Canc Ctr, Dallas, TX 75390 USA.

CELL REPORTS, 2017; 20 (5): 1088

Abstract

Modification of nucleocytoplasmic proteins with O-GlcNAc regulates a wide variety of cellular processes and has been linked to human diseases. The enz......

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