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IDE Degrades Nociceptin/Orphanin FQ through an Insulin Regulated Mechanism

Zingale, GA; Bellia, F; Ahmed, IMM; Mielczarek, P; Silberring, J; Grasso, G

Grasso, G (reprint author), Univ Catania, Dept Chem Sci, I-95125 Catania, Italy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019; 20 (18):

Abstract

Insulin-degrading enzyme (IDE) was applied to catalyze hydrolysis of Nociceptin/Orphanin 1-16 (OFQ/N) to show the involvement of the enzyme in degrada......

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