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Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5

Lai, GR; Wang, LT; Li, Z; Zhao, YY

Zhao, YY (corresponding author), China Med Univ, Dept Clin Genet, Shengjing Hosp, Shenyang, Liaoning, Peoples R China.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2020; 319 (6): H1380

Abstract

Homocysteine (Hcy) is an independent risk factor of congenital heart disease (CHD), but its exact underlying mechanism is unclear. In this study, we c......

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