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Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3

Chen, XJ; Xu, Y; Tu, WH; Huang, F; Zuo, YB; Zhang, HG; Jin, LC; Feng, Q; Ren, TF; He, JY; Miao, Y; Yuan, YK; Zhao, Q; Liu, JP; Zhang, RX; Zhu, L; Qian, F; Zhu, CW; Zheng, H; Wang, J

Zheng, H (corresponding author), Soochow Univ, Inst Biol & Med Sci, Jiangsu Key Lab Infect & Immun, Suzhou 215123, Peoples R China.; Wang, J (corresponding author), Soochow Univ, Affiliated Hosp 1, Dept Intens Care Med, Suzhou 215006, Peoples R China.

IMMUNOLOGY, ; ():

Abstract

Interferon regulatory factor 3 (IRF3) is a critical transcription factor for inducing production of type I interferons (IFN-I) and regulating host ant......

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