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Bi-allelic SPATA22 variants cause premature ovarian insufficiency and nonobstructive azoospermia due to meiotic arrest

Yao, CC; Hou, D; Ji, ZY; Pang, DM; Li, P; Tian, RH; Zhang, YX; Ou, NJ; Bai, HW; Zhi, EL; Huang, YH; Qin, YY; Zhao, JP; Wang, CC; Zhou, Z; Guo, T; Li, Z

Li, Z (通讯作者),Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Sch Med,Shanghai Key Lab Reprod Med, Dept Androl,Ctr Mens Hlth,Dept ART,Inst Urol,Urol, Shanghai 200080, Peoples R China.;Zhou, Z (通讯作者),ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China.;Guo, T (通讯作者),Shandong Univ, Ctr Reprod Med, Natl Res Ctr Assisted Reprod Technol & Reprod Gen, Key Lab Reprod Endocrinol,Minist Educ, Jinan 250012, Peoples R China.;Guo, T (通讯作者),Shandong Prov Clin Med Res Ctr Reprod Hlth, Jinan

CLINICAL GENETICS, 2022; 101 (5-6): 507

Abstract

The genetic causes of idiopathic premature ovarian insufficiency (POI) and nonobstructive azoospermia (NOA) remain unclear. We performed whole-exome s......

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