Intrathecal administration of the extracellular vesicles derived from human Wharton's jelly stem cells inhibit inflammation and attenuate the activity of inflammasome complexes after spinal cord injury in rats-MedSci.cn

Intrathecal administration of the extracellular vesicles derived from human Wharton's jelly stem cells inhibit inflammation and attenuate the activity of inflammasome complexes after spinal cord injury in rats

Noori, L; Arabzadeh, S; Mohamadi, Y; Mojaverrostami, S; Mokhtari, T; Akbari, M; Hassanzadeh, G

Hassanzadeh, G (corresponding author), Univ Tehran Med Sci, Sch Med, Dept Anat, Tehran, Iran.; Hassanzadeh, G (corresponding author), Univ Tehran Med Sci, Sch Adv Technol Med, Dept Neurosci & Addict Studies, Tehran, Iran.; Hassanzadeh, G (corresponding author), Legal Med Org, Legal Med Res Ctr, Tehran, Iran.

Abstract

Activation of inflammasome complexes during spinal cord injury (SCI) lead to conversion of pro inflammatory cytokines, interleukin-1beta (IL-1 beta) a......

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Intrathecal administration of the extracellular vesicles derived from human Wharton's jelly stem cells inhibit inflammation and attenuate the activity of inflammasome complexes after spinal cord injury in rats

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