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Backbone-Fluorinated 1,2,3-Triazole-Containing Dipeptide Surrogates

Engel-Andreasen, J; Wellhofer, I; Wich, K; Olsen, CA

Olsen, CA (reprint author), Univ Copenhagen, Ctr Biopharmaceut, Fac Hlth & Med Sci, Univ Pk 2, DK-2100 Copenhagen, Denmark.

JOURNAL OF ORGANIC CHEMISTRY, 2017; 82 (21): 11613

Abstract

The 1,2,3-triazole moiety can be incorporated as a peptide bond bioisostere to provide protease resistance in peptidomimetics. Herein, we report the s......

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