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MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment

Haschka, MD; Karbon, G; Soratroi, C; O'Neill, KL; Luo, X; Villunger, A

Villunger, A (corresponding author), Med Univ Innsbruck, Bioctr, Inst Dev Immunol, A-6020 Innsbruck, Austria.; Villunger, A (corresponding author), Ludwig Boltzmann Inst Rare & Undiagnosed Dis, A-1090 Vienna, Austria.; Villunger, A (corresponding author), Austrian Acad Sci, CeMM Res Ctr Mol Med, A-1090 Vienna, Austria.

CELL DEATH AND DIFFERENTIATION, 2020; 27 (8): 2297

Abstract

Cells experiencing delays in mitotic progression are prone to undergo apoptosis unless they can exit mitosis before proapoptotic factors reach a criti......

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