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Trimethylamine N-oxygenation in cynomolgus macaques genotyped for flavin-containing monooxygenase 3 (FMO3)

Shimizu, M; Uno, Y; Utoh, M; Yamazaki, H

Yamazaki, H (corresponding author), Showa Pharmaceut Univ, Lab Drug Metab & Pharmacokinet, 3-3165 Higashi Tamagawa Gakuen, Machida, Tokyo 1948543, Japan.; Uno, Y (corresponding author), Kagoshima Univ, Joint Fac Vet Med, 1-21-24 Korimoto, Kagoshima, Kagoshima 8908580, Japan.

DRUG METABOLISM AND PHARMACOKINETICS, 2020; 35 (6): 571

Abstract

Polymorphic human and cynomolgus macaque flavin-containing monooxygenases (FMO) 3 are important oxygenation enzymes for nitrogen-containing drugs. Int......

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