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The E3 Ligase MIB1 Promotes Proteasomal Degradation of NRF2 and Sensitizes Lung Cancer Cells to Ferroptosis

Wang, HY; Huang, QL; Xia, JH; Cheng, S; Pei, DQ; Zhang, XF; Shu, XD

Shu, XD (通讯作者),Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China.

MOLECULAR CANCER RESEARCH, 2022; 20 (2): 253

Abstract

Dysregulation of Notch signaling has been implicated in cellular transformation and tumorigenesis in a variety of cancers while potential roles of MIB......

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