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Effect of uridine protecting groups on the diastereoselectivity of uridine-derived aldehyde 5'-alkynylation

Ben Othman, R; Fer, MJ; Le Corre, L; Calvet-Vitale, S; Gravier-Pelletier, C

Calvet-Vitale, S; Gravier-Pelletier, C (reprint author), Univ Paris 05, Sorbonne Paris Cite USPC, CICB Paris, Lab Chim & Biochim Pharmacol & Toxicol,UMR CNRS 8, 45 St Peres, F-75270 Paris 06, France.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2017; 13 ( ): 1533

Abstract

The 5'-alkynylation of uridine-derived aldehydes is described. The addition of alkynyl Grignard reagents on the carbonyl group is significantly influe......

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