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Higher Order Oligomerization of the Licensing ORC4 Protein Is Required for Polar Body Extrusion in Murine Meiosis

Nguyen, H; James, NG; Nguyen, L; Nguyen, TP; Vuong, C; Ortega, MA; Jameson, DM; Ward, WS

Ward, WS (reprint author), Univ Hawaii Manoa, Dept Anat Biochem & Physiol, Inst Biogenesis Res, John A Burns Sch Med, 1960 East West Rd, Honolulu, HI 96822 USA.; Ward, WS (reprint author), Univ Hawaii Manoa, John A Burns Sch Med, Div Res, 1960 East West R

JOURNAL OF CELLULAR BIOCHEMISTRY, 2017; 118 (9): 2941

Abstract

We have previously shown that the DNA replication licensing factor ORC4 forms a cage around the chromosomes that are extruded in both polar bodies dur......

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