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Dust fall PM2.5-induced lung inflammation in rats is associated with hypermethylation of the IFN-? gene promoter via the PI3K-Akt-DNMT3b pathway

Bai, J; Wang, HL; Yang, SY; Lu, J; Li, CW; Sun, YC; Huo, TT; Deng, JJ; Zhang, QB

Zhang, QB (通讯作者),Southwest Med Univ, Sch Publ Hlth, Luzhou 646000, Peoples R China.;Deng, JJ (通讯作者),404 Hosp Mianyang, Dept Clin Lab, Mianyang 621000, Peoples R China.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2022; 95 ():

Abstract

Inflammation is one of the major adverse effects of fine particulate matter (PM2.5) on the lung system; however, its mechanisms remain unclear. Rats w......

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