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Asymmetric synthesis of vicinal amino alcohols via organocatalytic sequential alpha-amination/Grignard addition reactions of aldehydes

Liu, C; Weng, J; Lin, ZH; Huang, WJ; Guo, J; Huang, LJ; Lu, G

Weng, J; Lu, G (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Inst Med Chem, Guangzhou 510006, Guangdong, Peoples R China.; Lu, G (reprint author), Sun Yat Sen Univ, Inst Human Virol, Guangzhou 510080, Guangdong, Peoples R China.

TETRAHEDRON-ASYMMETRY, 2017; 28 (1): 41

Abstract

An organocatalytic sequential alpha-amination/Grignard addition reaction of aliphatic aldehydes is reported. The synthetically useful anti-vicinal ami......

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