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An integrative analysis of DNA methylation and transcriptome showed the dysfunction of MAPK pathway was involved in the damage of human chondrocyte induced by T-2 toxin

Yang, XN; Xiao, X; Zhang, L; Wang, B; Li, P; Cheng, BL; Liang, CJ; Ma, M; Guo, X; Zhang, F; Wen, Y

Wen, Y (通讯作者),Xi An Jiao Tong Univ, Hlth Sci Ctr, Collaborat Innovat Ctr Endem Dis & Hlth Promot Si, Key Lab Trace Elements & Endem Dis,Sch Publ Hlth, Xian 710061, Shaanxi, Peoples R China.

BMC MOLECULAR AND CELL BIOLOGY, 2022; 23 (1):

Abstract

Background T-2 toxin is thought to induce the growth plate and articular cartilage damage of Kashin-Beck disease (KBD), an endemic osteochondropathy i......

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