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Potent Triazolopyridine Myeloperoxidase Inhibitors

Wurtz, NR; Viet, A; Shaw, SA; Dilger, A; Valente, MN; Khan, JA; Jusuf, S; Narayanan, R; Fernando, G; Lo, F; Liu, XQ; Locke, GA; Kopcho, L; Abell, LM; Sleph, P; Basso, M; Zhao, L; Wexler, RR; Duclos, F; Kick, EK

Wurtz, NR (reprint author), Bristol Myers Squibb Res & Dev, POB 5400, Princeton, NJ 08534 USA.

ACS MEDICINAL CHEMISTRY LETTERS, 2018; 9 (12): 1175

Abstract

Myeloperoxidase (MPO) generates reactive oxygen species that potentially contribute to many chronic inflammatory diseases. A recently reported triazol......

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