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Synthesis and antiproliferative activity of 3-hydroxyl-3-methoxymethyl-5-pregnan-20-one with a C-21 hydrophilic substituent

Tsai, SE; Lee, JC; Uramaru, N; Takayama, H; Huang, GJ; Wong, FF

Wong, FF (reprint author), China Med Univ, Sch Pharm, Taichung, Taiwan.

HETEROATOM CHEMISTRY, 2017; 28 (3):

Abstract

A series of 3-hydroxyl-3-methoxymethyl-5-pregnan-20-ones 7-15 possessing C-21 hydrophilic substituents were synthesized from the corresponding C21-bro......

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