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Sodium borohydride and thiol mediated nitrite release from nitroaromatic antibiotics

Rice, AM; Faig, A; Wolff, DE; King, SB

King, SB (corresponding author), Wake Forest Univ, Dept Chem, Winston Salem, NC 27101 USA.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 48 ():

Abstract

Nitroaromatic antibiotics are used to treat a variety of bacterial and parasitic infections. These prodrugs require reductive bioactivation for activi......

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