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Neurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline

Ortiz, CC; Neal, AM; Avrutsky, MI; Choi, M; Smart, J; Lawson, J; Troy, CM

Troy, CM (通讯作者),Columbia Univ, Dept Pathol & Cell Biol, New York, NY 10032 USA.;Troy, CM (通讯作者),Columbia Univ, Vagelos Coll Phys & Surg, New York, NY 10032 USA.;Troy, CM (通讯作者),Columbia Univ, Dept Neurol, New York, NY 10032 USA.;Troy, CM (通讯作者),Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA.

CELL DEATH & DISEASE, 2022; 13 (11):

Abstract

Retinal neurovascular injuries are a leading cause of vision loss in young adults presenting unmet therapeutic needs. Neurovascular injuries damage ho......

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