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Jerveratrum-Type Steroidal Alkaloids Inhibit beta-1,6-Glucan Biosynthesis in Fungal Cell Walls

Kubo, K; Itto-Nakama, K; Ohnuki, S; Yashiroda, Y; Li, SC; Kimura, H; Kawamura, Y; Shimamoto, Y; Tominaga, KI; Yamanaka, D; Adachi, Y; Takashima, S; Noda, Y; Boone, C; Ohya, Y

Itto-Nakama, K; Ohya, Y (通讯作者)，Univ Tokyo, Grad Sch Frontier Sci, Dept Integrated Biosci, Kashiwa, Chiba, Japan.;Ohya, Y (通讯作者)，Natl Inst Adv Ind Sci & Technol, AIST UTokyo Adv Operando Measurement Technol Open, Kashiwa, Chiba, Japan.;Ohya, Y (通讯作者)，Univ Tokyo, Collaborat Res Inst Innovat Microbiol, Bunkyo Ku, Tokyo, Japan.

MICROBIOLOGY SPECTRUM, 2022; 10 (1):

Abstract

The limited number of available effective agents necessitates the development of new antifungals. We report that jervine, a jerveratrum-type steroidal......

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