RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma-MedSci.cn

RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma

Yang, TW; Zhu, CL; Shi, Y; Shen, YT; Gao, YX; Zhang, BW; Jin, RF; Liu, DJ; Ouyang, YB; Liu, XN; Wang, WJ; Yang, PX; Xu, QG; Cai, JZ; Chen, DX

Xu, QG; Cai, JZ; Chen, DX (通讯作者)，Qingdao Univ, Organ Transplantat Ctr, Affiliated Hosp, Qingdao 266003, Peoples R China.;Chen, DX (通讯作者)，Capital Med Univ, Beijing Inst Hepatol, Beijing 100069, Peoples R China.

Abstract

The Apoptosis Stimulating Protein of p53 2 (ASPP2) is a heterozygous insufficient tumor suppressor; however, its molecular mechanism(s) in tumor suppr......

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RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma

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