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The positive regulation loop between NRF1 and NONO-TFE3 fusion promotes phase separation and aggregation of NONO-TFE3 in NONO-TFE3 tRCC

Wang, B; Gan, WD; Han, XD; Liu, N; Ma, T; Li, DM

Li, DM (corresponding author), Nanjing Univ, Med Sch, Immunol & Reprod Biol Lab, Nanjing 210093, Jiangsu, Peoples R China.; Li, DM (corresponding author), Nanjing Univ, Med Sch, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China.; Gan, WD (corresponding author), Nanjing Univ, Med Sch, Affiliated Drum Tower Hosp, Dept Urol, Nanjing 210008, Jiangsu, Peoples R China.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021; 176 (): 437

Abstract

TFE3 gene fusions often place TFE3 under the control of amore active promoter and cause overexpression of the TFE3 proteins in renal cell carcinoma as......

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