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Capecitabine bioequivalence in healthy volunteers

Matos, MM; Bosio-Guimaraes, RA; Niederauer, AJS; Pastre, KIF; Moreno, RA; Schramm, SG; Galvinas, PAR; Mendes, GD; De Nucci, G

Mendes, GD (reprint author), 415 Jesuino Marcondes Machado Ave, BR-13092320 Campinas, SP, Brazil.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2018; 56 (10): 482

Abstract

Capecitabine is a prodrug and is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil, by thymidine phosphorylase, which is ge......

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