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Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging

Bejarano, E; Murray, JW; Wang, XT; Pampliega, O; Yin, D; Patel, B; Yuste, A; Wolkoff, AW; Cuervo, AM

Wolkoff, AW (reprint author), Albert Einstein Coll Med, Dept Anat & Struct Biol, Bronx, NY 10461 USA.; Bejarano, E (reprint author), JeanMayer USDA Human Nutr Res Ctr Aging, Lab Nutr & Vision Res, Boston, MA 02111 USA.

AGING CELL, 2018; 17 (4):

Abstract

Inability to preserve proteostasis with age contributes to the gradual loss of function that characterizes old organisms. Defective autophagy, a compo......

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