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Chronic ghrelin administration suppresses IKK/NF-kappa B/BACE1 mediated A beta production in primary neurons and improves cognitive function via upregulation of PP1 in STZ-diabetic rats

Ma, LY; Liu, SF; Du, JH; Niu, Y; Hou, PF; Shu, Q; Ma, RR; Wu, SD; Qu, QM; Lv, YL

Wu, SD (corresponding author), First Hosp Xian, Dept Neurol, Xian, Peoples R China.; Qu, QM (corresponding author), Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Neurol, Xian, Peoples R China.; Lv, YL (corresponding author), Fourth Hosp Xian, Dept Neurol, Xian, Peoples R China.

NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 169 ():

Abstract

Diabetic rats display cognition impairments accompanied by activation of NF-kappa B signalling and increased A beta expression. Ghrelin has been sugge......

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