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A Divergent Route to Eravacycline

Zhang, WY; Che, QL; Crawford, S; Ronn, M; Dunwoody, N

Zhang, WY (reprint author), Tetraphase Pharmaceut Inc, 480 Arsenal Way,Suite 110, Watertown, MA 02472 USA.

JOURNAL OF ORGANIC CHEMISTRY, 2017; 82 (2): 936

Abstract

A convergent route to eravacycline (1) has been developed by employing Michael Dieckmann cyclization between enone 3 and a fully built and protected l......

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