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The methyltransferase PRMT1 regulates gamma-globin translation

Wang, Y; Li, XY; Ge, JR; Liu, M; Pang, XM; Liu, JP; Luo, C; Xu, YC; Zhao, Q

Zhao, Q (corresponding author), Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Dept Hematol,Sch Life Sci, Affiliated Drum Tower Hosp,Med Sch,China Australi, Nanjing, Peoples R China.; Xu, YC (corresponding author), Univ Calif San Francisco, Dept Urol, San Francisco, CA 94110 USA.; Xu, YC (corresponding author), Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA.; Xu, YC (corresponding author), Zhejiang Univ, Coll Pharmaceut Sci, Zhejiang Prov Key L

JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ():

Abstract

Induction of fetal hemoglobin to overcome adult beta-globin gene deficiency is an effective therapeutic strategy to ameliorate human beta-hemoglobinop......

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