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Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

Zhou, XM; Du, JF; Wang, HF; Chen, CX; Jiao, L; Cheng, XR; Zhou, XW; Chen, SM; Gou, SS; Zhao, WS; Zhai, WJ; Chen, JH; Gao, YF

Chen, JH; Gao, YF (corresponding author), Peking Univ, Intervent & Cell Therapy Ctr, Shenzhen Hosp, Shenzhen Peking Univ Hong Kong Univ Sci & Technol, Shenzhen 518035, Peoples R China.

CELL COMMUNICATION AND SIGNALING, 2020; 18 (1):

Abstract

Background: Inhibitors targeting immune checkpoint were proved effective in cancer immunotherapy, such as PD-1/PD-L1 blockade. The novel immune checkp......

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