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Activation of the HSP27-AKT axis contributes to gefitinib resistance in non-small cell lung cancer cells independent of EGFR mutations

Choi, SK; Kim, M; Lee, H; Kwon, Y; Cha, HJ; Jang, SJ; Na, Y; Lee, YS

Lee, YS (通讯作者),Ewha Womans Univ, Grad Sch Pharmaceut Sci, 52 Ewhayeodae Gil, Seoul 120720, South Korea.;Na, Y (通讯作者),CHA Univ, Coll Pharm, 120 Haeryong Ro, Pochon 487010, South Korea.

CELLULAR ONCOLOGY, 2022; 45 (5): 913

Abstract

Purpose Although epidermal growth factor receptor (EGFR)-activating mutations in non-small cell lung cancer (NSCLC) usually show sensitivity to first-......

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