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A single, oral dose of the TLR7 agonist JNJ-64794964 induces transcriptomic and phenotypic changes in peripheral immune cells in healthy adults

Pierson, W; Tuefferd, M; Herschke, F; Slaets, L; Crabbe, M; Verstappen, D; De Pelsmaeker, S; Strickland, I; Gane, EJ; Schwabe, C; Zhang, YJ; Meerts, P; Vandenbossche, J; Van Remoortere, P; Verbrugge, I; De Creus, A

Verbrugge, I (通讯作者),Janssen Pharmaceut NV, Beerse, Belgium.

ANTIVIRAL THERAPY, 2023; 28 (3):

Abstract

BackgroundChronic hepatitis B (CHB) is responsible for major disease burden worldwide. However, the number of available therapies is limited; cure rem......

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