Massively parallel CRISPR off-target detection enables rapid off-target prediction model building-MedSci.cn

Massively parallel CRISPR off-target detection enables rapid off-target prediction model building

Tian, R; Cao, C; He, D; Dong, DR; Sun, LL; Liu, JS; Chen, Y; Wang, YY; Huang, ZY; Li, LF; Jin, Z; Huang, ZY; Xie, HX; Zhao, TT; Zhong, CY; Hong, YF; Hu, Z

Tian, R (通讯作者)，Generulor Co Ltd, Zhuhai 519000, Guangdong, Peoples R China.;Hu, Z (通讯作者)，Wuhan Univ, Women & Childrens Hosp, Zhongnan Hosp, Dept Gynecol Oncol, Wuhan 430071, Hubei, Peoples R China.;Hu, Z (通讯作者)，Wuhan Univ, Zhongnan Hosp, Dept Radiat & Med Oncol, Wuhan 430071, Hubei, Peoples R China.;Hu, Z (通讯作者)，Wuhan Univ, Zhongnan Hosp, Hubei Key Lab Tumor Biol Behav, Wuhan 430071, Hubei, Peoples R China.;Hu, Z (通讯作者)，Wuhan Univ, Zhongnan Hosp, Hubei Canc Clin Study Ctr, Wuhan 430071, Hubei, Peoples R China.

MED, 2023; 4 (7): 478

Abstract

Background: CRISPR (clustered regularly interspaced short palindromic repeats) genome editing holds tremendous potential in clinical translation. Howe......

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Massively parallel CRISPR off-target detection enables rapid off-target prediction model building

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